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Article

Dubin-Johnson syndrome coinciding with colon cancer and atherosclerosis.

World journal of gastroenterology - 14 Feb 2013

Sticova Eva, Elleder Milan, Hulkova Helena, Luksan Ondrej, Sauer Martin, Wunschova-Moudra Irena, Novotny Jan, Jirsa Milan

Abstract excerpt

Hyperbilirubinemia has been presumed to prevent the process of atherogenesis and cancerogenesis mainly by decreasing oxidative stress. Dubin-Johnson syndrome is a rare, autosomal recessive, inherited disorder characterized by biphasic, predominantly conjugated hyperbilirubinemia with no progressi...

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Source

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Identifiers

PMID: 23429660
DOI: 10.3748/wjg.v19.i6.946
PMCID: PMC3574894

Genes

ABCC2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23429660-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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Dubin-Johnson syndrome coinciding with colon cancer and atherosclerosis.PMID 23429660Read ↗

Concurrence of novel mutations causing Gilbert's and Dubin-Johnson syndrome with poor clinical outcomes in a Han Chinese family.Semantic proximity Read ↗

A recurrent ABCC2 p.G693R mutation resulting in loss of function of MRP2 and hyperbilirubinemia in Dubin-Johnson syndrome in ChinaSemantic proximity Read ↗

Genetic contribution of ABCC2 to Dubin‐Johnson syndrome and inherited cholestatic disordersSemantic proximity Read ↗

A recurrent ABCC2 p.G693R mutation resulting in loss of function of MRP2 and hyperbilirubinemia in Dubin-Johnson syndrome in China.Semantic proximity Read ↗

Novel mutations in the Dubin-Johnson syndrome gene ABCC2/MRP2 and associated biochemical changes.Semantic proximity Read ↗

[Genetic analysis of a case with Dubin-Johnson syndrome due to two novel variants of ABCC2 gene].Semantic proximity Read ↗

[Clinical and molecular genetic analysis of nine patients with neonatal Dubin-Johnson syndrome].Semantic proximity Read ↗

Characterization of a novel ABCC2 mutation in infantile Dubin Johnson syndrome.Semantic proximity Read ↗

Genetic and biochemical study of dual hereditary jaundice: Dubin-Johnson and Gilbert's syndromes. Haplotyping and founder effect of deletion in ABCC2.Semantic proximity Read ↗

Exon-intron organization of the human multidrug-resistance protein 2 (MRP2) gene mutated in Dubin-Johnson syndrome.Semantic proximity Read ↗

[The phenotypes and genotypes of four patients with Dubin-Johnson syndrome].Semantic proximity Read ↗

In silico screening and analysis of single-nucleotide polymorphic variants of the ABCC2 gene affecting Dubin-Johnson syndrome.Semantic proximity Read ↗

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