Article
Impact of microbes on autoimmune diseases.
Archivum immunologiae et therapiae experimentalis - 1 Jun 2013
Danzer Claudia, Mattner Jochen
Abstract excerpt
Autoimmune and autoinflammatory diseases arise as a consequence of complex interactions of environmental factors with genetic traits. Although specific allelic variations cluster in predisposed individuals and promote the generation and/or expansion of autoreactive T and B lymphocytes, autoimmunity appears in various disease phenotypes and localizes to diverging tissues. Furthermore, the discovery that allelic...
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