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Article

Gaussian process-based Bayesian nonparametric inference of population size trajectories from gene genealogies.

Biometrics - 1 Mar 2013

Palacios Julia A, Minin Vladimir N

Abstract excerpt

Changes in population size influence genetic diversity of the population and, as a result, leave a signature of these changes in individual genomes in the population. We are interested in the inverse problem of reconstructing past population dynamics from genomic data. We start with a standard framework based on the coalescent, a stochastic process that generates genealogies connecting randomly sampled...

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PMID: 23409705
DOI: 10.1111/biom.12003

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