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A decade of plague in Mahajanga, Madagascar: insights into the global maritime spread of pandemic plague.

mBio - 12 Feb 2013

Vogler Amy J, Chan Fabien, Nottingham Roxanne, Andersen Genevieve, Drees Kevin, Beckstrom-Sternberg Stephen M, Wagner David M, Chanteau Suzanne, Keim Paul

Abstract excerpt

UNLABELLED: A cluster of human plague cases occurred in the seaport city of Mahajanga, Madagascar, from 1991 to 1999 following 62 years with no evidence of plague, which offered insights into plague pathogen dynamics in an urban environment. We analyzed a set of 44 Mahajanga isolates from this 9-year outbreak, as well as an additional 218 Malagasy isolates from the highland foci. We sequenced the genomes of four...

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Identifiers

PMID: 23404402
DOI: 10.1128/mBio.00623-12
PMCID: PMC3573667

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