Article
Multifocal white matter lesions associated with the D313Y mutation of the α-galactosidase A gene.
PloS one - 1 Jan 2013
Lenders Malte, Duning Thomas, Schelleckes Michael, Schmitz Boris, Stander Sonja, Rolfs Arndt, Brand Stefan-Martin, Brand Eva
Abstract excerpt
White matter lesions (WML) are clinically relevant since they are associated with strokes, cognitive decline, depression, or epilepsy, but the underlying etiology in young adults without classical risk factors still remains elusive. Our aim was to elucidate the possible clinical diagnosis and mechanisms leading to WML in patients carrying the D313Y mutation in the α-galactosidase A (GLA) gene, a mutation that was...
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