Article
Epidermal growth factor receptor tyrosine kinase inhibitors in the treatment of NSCLC.
Lung cancer (Amsterdam, Netherlands) - 1 May 2013
Pallis A G, Syrigos K N
Abstract excerpt
Improvements in our understanding of the molecular biology of cancer have shifted management of lung cancer toward molecular-guided, individualized treatment. Development of epidermal growth factor receptor tyrosine kinase inhibitors, erlotinib and gefitinib, represent the best example of this approach. Erlotinib was tested as second/third line treatment in unselected population of patients and demonstrated a...
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