Article
The human microbiome and autoimmunity.
Current opinion in rheumatology - 1 Mar 2013
Proal Amy D, Albert Paul J, Marshall Trevor G
Abstract excerpt
PURPOSE OF REVIEW: To demonstrate how dysbiosis of the human microbiome can drive autoimmune disease. RECENT FINDINGS: Humans are superorganisms. The human body harbors an extensive microbiome, which has been shown to differ in patients with autoimmune diagnoses. Intracellular microbes slow innate immune defenses by dysregulating the vitamin D nuclear receptor, allowing pathogens to accumulate in tissue and...
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