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Article

Hepatitis E virus isolated from rabbits is genetically heterogeneous but with very similar antigenicity to human HEV.

Journal of medical virology - 1 Apr 2013

Wang Song, Dong Chen, Dai Xing, Cheng Xianfeng, Liang Jiuhong, Dong Min, Purdy Michael A, Meng Jihong

Abstract excerpt

Rabbit hepatitis E virus (HEV) in China may represent a novel HEV genotype, although no consensus has been reached. It is unclear whether the ORF2 capsid protein containing the immunodominant epitopes from rabbit HEV differs from those of human HEV. In this study, 661 bile samples collected from domestic rabbits in Jiangsu province, eastern China were amplified by RT-nPCR using a set of HEV universal ORF2...

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PMID: 23364756
DOI: 10.1002/jmv.23504

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