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Gene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans

9 Jan 2013

Abstract excerpt

Staphylococcus aureus causes a spectrum of human infection. Diagnostic delays and uncertainty lead to treatment delays and inappropriate antibiotic use. A growing literature suggests the host's inflammatory response to the pathogen represents a potential tool to improve upon current diagnostics. The hypothesis of this study is that the host responds differently to S. aureus than to E. coli infection in a...

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PMID: 23326304
DOI: 10.1371/journal.pone.0048979

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