Article
[Efficacy of low-dose erlotinib against gefitinib-induced hepatotoxicity in a patient with lung adenocarcinoma harboring EGFR mutations].
Gan to kagaku ryoho. Cancer & chemotherapy - 1 Jan 2013
Kitade Hironori, Yamada Tadaaki, Igarashi Saya, Hokkoku Kengo, Mori Mitsue, Shintaku Kimiko, Sagawa Motoyasu, Nakai Masuo, Yano Seiji
Abstract excerpt
We report a case of a female in her 80s who was diagnosed with recurrent lung adenocarcinoma after primary surgery. She was treated with a systemic chemotherapy regimen consisting of carboplatin plus paclitaxel until the disease showed progression. On detection of epidermal growth factor receptor(EGFR)mutations, we administered gefitinib, an EGFR tyrosine kinase inhibitor, at a dosage of 250 mg daily. After 6...
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