Article
Spatial subdivision of populations and estimates of genetic variation.
Theoretical population biology - 1 Feb 1990
Cavalli-Sforza L L, Feldman M W
Abstract excerpt
Measures of variation in space are strongly affected by correlations between subdivisions used for sampling. Here we consider variation in gene frequencies across populations. Usually the variance of gene frequencies is standardized by dividing it by the mean gene frequency times one minus the mean (FST). Under the model of isolation by distance (usually called the "stepping stone" model), at the stationary state...
Topics
- Blood Group Antigens
- Gene Frequency
- Genetic Carrier Screening
- Genetic Variation
- Genetics, Population
- Humans
- Italy
- Models, Genetic