Article
Linkage analysis of a large African family segregating stuttering suggests polygenic inheritance.
Human genetics - 1 Apr 2013
Raza M Hashim, Gertz E Michael, Mundorff Jennifer, Lukong Joseph, Kuster Judith, Schäffer Alejandro A, Drayna Dennis
Abstract excerpt
We describe a pedigree of 71 individuals from the Republic of Cameroon in which at least 33 individuals have a clinical diagnosis of persistent stuttering. The high concentration of stuttering individuals suggests that the pedigree either contains a single highly penetrant gene variant or that assortative mating led to multiple stuttering-associated variants being transmitted in different parts of the pedigree....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.