Article
[Epidural labor analgesia and parturient with type 2B von Willebrand disease].
Annales francaises d'anesthesie et de reanimation - 1 Jan 2013
Lagarrigue J, Richez B, Julliac B, Saltel L, Nurden P, Sztark F
Abstract excerpt
Type 2B von Willebrand disease (vWD) is an inherited bleeding syndrome resulting from a qualitative abnormality of von Willebrand Factor with an increased affinity for the glycoprotein Ib platelet receptor. Pregnancy increases the severity of this disease by decreasing the platelet count restricting epidural anaesthesia because of adverse risk of spinal bleeding. There is a phenotypic variability of Type 2B vWD...
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