Article
Colistin resistance in gram-negative bacteria during prophylactic topical colistin use in intensive care units.
Intensive care medicine - 1 Apr 2013
Oostdijk Evelien A N, Smits Loek, de Smet Anne Marie G A, Leverstein-van Hall Maurine A, Kesecioglu Jozef, Bonten Marc J M
Abstract excerpt
PURPOSE: Topical use of colistin as part of selective digestive decontamination (SDD) and selective oropharyngeal decontamination (SOD) has been associated with improved patient outcome in intensive care units (ICU), yet little is known about the risks of colistin resistance. We quantified effects of selective decontamination on acquisition of colistin-resistant gram-negative bacteria (GNB) using data from a...
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