Article
Dual oral therapy with daclatasvir and asunaprevir for patients with HCV genotype 1b infection and limited treatment options.
Journal of hepatology - 1 Apr 2013
Suzuki Yoshiyuki, Ikeda Kenji, Suzuki Fumitaka, Toyota Joji, Karino Yoshiyasu, Chayama Kazuaki, Kawakami Yoshiiku, Ishikawa Hiroki, Watanabe Hideaki, Hu Wenhua, Eley Timothy, McPhee Fiona, Hughes Eric, Kumada Hiromitsu
Abstract excerpt
BACKGROUND & AIMS: Improved therapeutic options for chronic hepatitis C virus (HCV) infection are needed for patients who are poor candidates for treatment with current regimens due to anticipated intolerability or low likelihood of response. METHODS: In this open-label, phase 2a study of Japanese patients with chronic HCV genotype 1b infection, 21 null responders (<2 log₁₀ HCV RNA reduction after 12 weeks of...
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