Article
Impact of passing mesenchymal stem cells through smaller bore size needles for subsequent use in patients for clinical or cosmetic indications.
Journal of translational medicine - 21 Nov 2012
Mamidi Murali Krishna, Singh Gurbind, Husin Juani Mazmin, Nathan Kavitha Ganesan, Sasidharan Gopinath, Zakaria Zubaidah, Bhonde Ramesh, Majumdar Anish Sen, Das Anjan Kumar
Abstract excerpt
BACKGROUND: Numerous preclinical and clinical studies have investigated the regenerative potential and the trophic support of mesenchymal stem cells (MSCs) following their injection into a target organ. Clinicians favor the use of smallest bore needles possible for delivering MSCs into vascular organs like heart, liver and spleen. There has been a concern that small needle bore sizes may be detrimental to the...
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