Article
Genomic consequences of transitions from cross- to self-fertilization on the efficacy of selection in three independently derived selfing plants.
BMC genomics - 12 Nov 2012
Ness Rob W, Siol Mathieu, Barrett Spencer C H
Abstract excerpt
BACKGROUND: Transitions from cross- to self-fertilization are associated with increased genetic drift rendering weakly selected mutations effectively neutral. The effect of drift is predicted to reduce selective constraints on amino acid sequences of proteins and relax biased codon usage. We investigated patterns of nucleotide variation to assess the effect of inbreeding on the accumulation of deleterious...
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