Article
Increased serum hepcidin levels in subjects with the metabolic syndrome: a population study.
PloS one - 1 Jan 2012
Martinelli Nicola, Traglia Michela, Campostrini Natascia, Biino Ginevra, Corbella Michela, Sala Cinzia, Busti Fabiana, Masciullo Corrado, Manna Daniele, Previtali Sara, Castagna Annalisa, Pistis Giorgio, Olivieri Oliviero, Toniolo Daniela, Camaschella Clara, Girelli Domenico
Abstract excerpt
The recent discovery of hepcidin, the key iron regulatory hormone, has changed our view of iron metabolism, which in turn is long known to be linked with insulin resistant states, including type 2 diabetes mellitus and the Metabolic Syndrome (MetS). Serum ferritin levels are often elevated in MetS (Dysmetabolic hyperferritinemia--DHF), and are sometimes associated with a true mild-to-moderate hepatic iron...
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