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Article

Heterozygosity assessment of five STR loci located at 5q13 region for preimplantation genetic diagnosis of spinal muscular atrophy.

Molecular biology reports - 1 Jan 2013

Korzebor Asghar, Derakhshandeh-Peykar Pupak, Meshkani Mohsen, Hoseini Azadeh, Rafati Maryam, Purhoseini Marzieh, Ghaffari Saeed Reza

Abstract excerpt

Preimplantation genetic diagnosis (PGD) has been considered as an alternative to prenatal diagnosis for prevention of genetic disorders while avoiding the subsequent termination of pregnancy. However, the limited amount of template DNA available in a single diploid cell used for PGD leads to number of problems including an increased incidence of detectable contamination; amplification failure and allele drop out....

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Source

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PMID: 23132709
DOI: 10.1007/s11033-012-2011-3

Genes

PGD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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