Article
The transcriptional landscape of the deep-sea bacterium Photobacterium profundum in both a toxR mutant and its parental strain.
BMC genomics - 29 Oct 2012
Campanaro Stefano, Pascale Fabio De, Telatin Andrea, Schiavon Riccardo, Bartlett Douglas H, Valle Giorgio
Abstract excerpt
BACKGROUND: The deep-sea bacterium Photobacterium profundum is an established model for studying high pressure adaptation. In this paper we analyse the parental strain DB110 and the toxR mutant TW30 by massively parallel cDNA sequencing (RNA-seq). ToxR is a transmembrane DNA-binding protein first discovered in Vibrio cholerae, where it regulates a considerable number of genes involved in environmental adaptation...
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