Article
Association between IL10, IL10RA, and IL10RB SNPs and ischemic stroke with hypertension in Korean population.
Molecular biology reports - 1 Feb 2013
Park Hyun-Kyung, Kim Dong Hwan, Yun Dong Hwan, Ban Ju Yeon
Abstract excerpt
The pathogenesis of stroke is associated with the immune and inflammatory responses. Cytokines, such as interleukin 10 (IL10), play an important role in the process of inflammation. To investigate whether IL10, IL10RA, and IL10RB polymorphisms are associated with the risk of ischemic stroke (IS), selected two IL10 SNPs (rs1518111 and rs1554286), three IL10RA SNPs (rs2256111, rs4252243, and rs2228054), and two...