Differences in microRNA Changes of Healthy Rat Liver between Sevoflurane and Propofol Anesthesia

Abstract excerpt

BACKGROUND: In previous studies, the authors showed that anesthetics affect the expression ratios of many genes in rat liver. microRNAs (miRNA) negatively regulate more than 30% of genes in cells, and control cell proliferation, inflammation, and metabolism. The authors hypothesized that anesthetics influence miRNA expression in the liver, and performed miRNA screening tests using TaqMan low-density arrays....

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