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Article

Survival and pregnancy outcome after ultrarapid freezing of human embryos

1 Jan 1991

Abstract excerpt

Contrary to the belief that rapid cooling and thawing of mammalian embryos is detrimental to survival, it has been shown that under certain conditions mammalian embryos can survive rapid freezing-thawing. In this study, 237 human fertilized oocytes (93 pronucleates, 20 multipronucleates, and 124 cleaved embryos) were frozen for a period of 1 day to 7 months using the ultrarapid freezing system. After thawing, 94%...

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PMID: 2307246
DOI: 10.1016/0020-7292(91)90572-m

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