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Article

Human papillomavirus genotypes in high-grade cervical lesions in the United States.

The Journal of infectious diseases - 15 Dec 2012

Hariri Susan, Unger Elizabeth R, Powell Suzanne E, Bauer Heidi M, Bennett Nancy M, Bloch Karen C, Niccolai Linda M, Schafer Sean, Steinau Martin, Markowitz Lauri E

Abstract excerpt

BACKGROUND: Two vaccines protect against human papillomaviruses (HPV) 16 and 18, which cause 70% of cervical cancer and 50% of cervical intraepithelial neoplasia 2/3 and adenocarcinoma in situ (CIN2+). Monitoring HPV types in CIN2+ may be used to assess HPV vaccine impact. METHODS: As part of a multisite vaccine impact monitoring project (HPV-IMPACT), biopsy specimens used to diagnose CIN2+ were obtained for HPV...

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PMID: 23045628
DOI: 10.1093/infdis/jis627
PMCID: PMC7506816

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