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Article

Heterogeneous subgroups among malignant diffuse small B cell lymphomas. A combined nucleometric and immunocytologic study.

Laboratory investigation; a journal of technical methods and pathology - 1 Feb 1990

Tosi P, Leoncini L, Del Vecchio M T, Cevenini G, Stramignoni A, Valente G, Palestro G, Novero D, Cottier H

Abstract excerpt

The degree of heterogeneity among subtypes was evaluated in 39 of the most frequent malignant, diffusely growing small B cell lymphomas by a combination of morphometry, automated image analysis, and immunocytologic techniques. Cluster analysis of nuclear profile parameters, including nuclear area, circularity factor, and chromatin distribution pattern, distinguished 3 groups. Each group was characterized by the...

Topics

Adult
Aged
B-Lymphocytes
Cell Nucleus
Chromatin
Female
Humans
Lymphoma, Non-Hodgkin
Male
Middle Aged
Phenotype

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PMID: 2304333

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2304333-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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