Mapping of a gene determining tuberous sclerosis to human chromosome 11q14-11q23.

doi:10.1016/0888-7543(90)90454-3

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Article

Mapping of a gene determining tuberous sclerosis to human chromosome 11q14-11q23.

Genomics - 1 Jan 1990

Smith M, Smalley S, Cantor R, Pandolfo M, Gomez M I, Baumann R, Flodman P, Yoshiyama K, Nakamura Y, Julier C

Abstract excerpt

Tuberous sclerosis (TSC) is a dominantly inherited disorder characterized by hamartomas and hamartias in one or more organs, most often in skin, brain, and kidneys. Analysis of the basic genetic defect in tuberous sclerosis would be greatly expedited by definitive determination of the chromosomal...

Topics

Alleles
Chromosome Mapping
Chromosomes, Human, Pair 11
Genetic Linkage
Humans
Lod Score
Pedigree
Tuberous Sclerosis

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