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Article

Reversible switching between epigenetic states in honeybee behavioral subcastes.

Nature neuroscience - 1 Oct 2012

Herb Brian R, Wolschin Florian, Hansen Kasper D, Aryee Martin J, Langmead Ben, Irizarry Rafael, Amdam Gro V, Feinberg Andrew P

Abstract excerpt

In honeybee societies, distinct caste phenotypes are created from the same genotype, suggesting a role for epigenetics in deriving these behaviorally different phenotypes. We found no differences in DNA methylation between irreversible worker and queen castes, but substantial differences between nurses and forager subcastes. Reverting foragers back to nurses reestablished methylation levels for a majority of...

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Identifiers

PMID: 22983211
DOI: 10.1038/nn.3218
PMCID: PMC3518384

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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