Article
Gene-targeted analysis of copy number variants identifies 3 novel associations with coronary heart disease traits.
Circulation. Cardiovascular genetics - 1 Oct 2012
Costelloe Seán J, El-Sayed Moustafa Julia S, Drenos Fotios, Palmen Jutta, Li Qiao, Qiao Li, Whiting Stephen, Thomas Michael, Kivimaki Mika, Kumari Meena, Hingorani Aroon D, Tzoulaki Ioanna, Järvelin Marjo-Riitta, Marjo-Riitta Järvelin, Ruokonen Aimo, Aimo Ruokonen, Hartikainen Anna-Liisa, Pouta Anneli, Walters Robin G, Blakemore Alexandra I F, Humphries Steve E, Coin Lachlan J M, Talmud Philippa J
Abstract excerpt
BACKGROUND: Copy number variants (CNVs) are a major form of genomic variation, which may be implicated in complex disease phenotypes. However, investigation of the role of CNVs in coronary heart disease (CHD) traits has been limited. METHODS AND RESULTS: We examined the use of the cnvHap algorith...
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