Article
Frequency matrix approach demonstrates high sequence quality in avian BARCODEs and highlights cryptic pseudogenes.
PloS one - 1 Jan 2012
Stoeckle Mark Y, Kerr Kevin C R
Abstract excerpt
The accuracy of DNA barcode databases is critical for research and practical applications. Here we apply a frequency matrix to assess sequencing errors in a very large set of avian BARCODEs. Using 11,000 sequences from 2,700 bird species, we show most avian cytochrome c oxidase I (COI) nucleotide and amino acid sequences vary within a narrow range. Except for third codon positions, nearly all (96%) sites were...
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