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Article

Extensive pyrosequencing reveals frequent intra-genomic variations of internal transcribed spacer regions of nuclear ribosomal DNA.

PloS one - 1 Jan 2012

Song Jingyuan, Shi Linchun, Li Dezhu, Sun Yongzhen, Niu Yunyun, Chen Zhiduan, Luo Hongmei, Pang Xiaohui, Sun Zhiying, Liu Chang, Lv Aiping, Deng Youping, Larson-Rabin Zachary, Wilkinson Mike, Chen Shilin

Abstract excerpt

BACKGROUND: Internal transcribed spacer of nuclear ribosomal DNA (nrDNA) is already one of the most popular phylogenetic and DNA barcoding markers. However, the existence of its multiple copies has complicated such usage and a detailed characterization of intra-genomic variations is critical to a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22952830
DOI: 10.1371/journal.pone.0043971
PMCID: PMC3431384

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22952830-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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