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Article

A gain-of-function polymorphism controlling complex traits and fitness in nature.

Science (New York, N.Y.) - 31 Aug 2012

Prasad Kasavajhala V S K, Song Bao-Hua, Olson-Manning Carrie, Anderson Jill T, Lee Cheng-Ruei, Schranz M Eric, Windsor Aaron J, Clauss Maria J, Manzaneda Antonio J, Naqvi Ibtehaj, Reichelt Michael, Gershenzon Jonathan, Rupasinghe Sanjeewa G, Schuler Mary A, Mitchell-Olds Thomas

Abstract excerpt

Identification of the causal genes that control complex trait variation remains challenging, limiting our appreciation of the evolutionary processes that influence polymorphisms in nature. We cloned a quantitative trait locus that controls plant defensive chemistry, damage by insect herbivores, survival, and reproduction in the natural environments where this polymorphism evolved. These ecological effects are...

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Identifiers

PMID: 22936775
DOI: 10.1126/science.1221636
PMCID: PMC3872477

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