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Article

Processing and subcellular trafficking of ER-tethered EIN2 control response to ethylene gas.

Science (New York, N.Y.) - 19 Oct 2012

Qiao Hong, Shen Zhouxin, Huang Shao-shan Carol, Schmitz Robert J, Urich Mark A, Briggs Steven P, Ecker Joseph R

Abstract excerpt

Ethylene gas is essential for many developmental processes and stress responses in plants. ETHYLENE INSENSITIVE2 (EIN2), an NRAMP-like integral membrane protein, plays an essential role in ethylene signaling, but its function remains enigmatic. Here we report that phosphorylation-regulated proteolytic processing of EIN2 triggers its endoplasmic reticulum (ER)-to-nucleus translocation. ER-tethered EIN2 shows...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22936567
DOI: 10.1126/science.1225974
PMCID: PMC3523706

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