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Article

Cytopathic effect of Acanthamoeba on human corneal fibroblasts.

Molecular vision - 1 Jan 2012

Takaoka-Sugihara Noriko, Yamagami Satoru, Yokoo Seiichi, Matsubara Masao, Yagita Kenji

Abstract excerpt

PURPOSE: Acanthamoeba keratitis is associated with keratocyte depletion in humans. We investigated how Acanthamoebae isolated from corneas affected by Acanthamoeba keratitis interacted with human corneal stromal cells in vitro. METHODS: Acanthamoebae were isolated from 6 patients with Acanthamoeba keratitis and genotyping was done. Whether the isolated Acanthamoebae could invade the corneal stroma was assessed...

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PMID: 22933834
PMCID: PMC3429359

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