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Article

Leptospira spp. strain identification by MALDI TOF MS is an equivalent tool to 16S rRNA gene sequencing and multi locus sequence typing (MLST).

BMC microbiology - 27 Aug 2012

Rettinger Anna, Krupka Inke, Grünwald Karola, Dyachenko Viktor, Fingerle Volker, Konrad Regina, Raschel Heribert, Busch Ulrich, Sing Andreas, Straubinger Reinhard K, Huber Ingrid

Abstract excerpt

BACKGROUND: In this study mass spectrometry was used for evaluating extracted leptospiral protein samples and results were compared with molecular typing methods. For this, an extraction protocol for Leptospira spp. was independently established in two separate laboratories. Reference spectra were created with 28 leptospiral strains, including pathogenic, non-pathogenic and intermediate strains. This set of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

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Identifiers

PMID: 22925589
DOI: 10.1186/1471-2180-12-185
PMCID: PMC3460781

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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