Article
Blood-based gene expression signatures of infants and toddlers with autism.
Journal of the American Academy of Child and Adolescent Psychiatry - 1 Sept 2012
Glatt Stephen J, Tsuang Ming T, Winn Mary, Chandler Sharon D, Collins Melanie, Lopez Linda, Weinfeld Melanie, Carter Cindy, Schork Nicholas, Pierce Karen, Courchesne Eric
Abstract excerpt
OBJECTIVE: Autism spectrum disorders (ASDs) are highly heritable neurodevelopmental disorders that onset clinically during the first years of life. ASD risk biomarkers expressed early in life could significantly impact diagnosis and treatment, but no transcriptome-wide biomarker classifiers derived from fresh blood samples from children with autism have yet emerged. METHOD: Using a community-based, prospective,...
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