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Article

Koi Herpesvirus Encodes and Expresses a Functional Interleukin-10

16 Aug 2012

Abstract excerpt

Koi herpesvirus (KHV) (species Cyprinid herpesvirus 3) ORF134 was shown to transcribe a spliced transcript encoding a 179-amino-acid (aa) interleukin-10 (IL-10) homolog (khvIL-10) in koi fin (KF-1) cells. Pairwise sequence alignment indicated that the expressed product shares 25% identity with carp IL-10, 22 to 24% identity with mammalian (including primate) IL-10s, and 19.1% identity with European eel...

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PMID: 22896613
DOI: 10.1128/jvi.00957-12

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