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Article

Variation in Candida albicans <i>EFG1</i> Expression Enables Host-Dependent Changes in Colonizing Fungal Populations

25 Jul 2012

Abstract excerpt

UNLABELLED: To understand differences in host-Candida albicans interactions that occur during colonization of healthy or compromised hosts, production of phenotypic variants and colonization of healthy or immunodeficient mice by C. albicans were studied. We showed that activity of the transcription factor Efg1p exhibited cell-to-cell variability and identified Efg1p as a major regulator of colonization. In C....

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PMID: 22829676
DOI: 10.1128/mbio.00117-12

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