Article
Cathepsin D as a potential prognostic marker for lung adenocarcinoma.
Pathology, research and practice - 15 Sept 2012
Mimae Takahiro, Tsuta Koji, Maeshima Akiko M, Okada Morihito, Asamura Hisao, Kondo Tadashi, Tsuda Hitoshi
Abstract excerpt
We previously identified cathepsin D as a possible marker for lung adenocarcinoma (AD). The purpose of the present study is to evaluate the correlation between cathepsin D expression and clinicopathological findings or prognosis. We conducted immunohistochemistry (IHC) to assess 150 AD tissues. For these 150 tumors, TTF-1 expression, EGFR and KRAS gene mutations, and ALK rearrangements had already been examined....
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