Article
Do small airway abnormalities characterize asthma phenotypes? In search of proof.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Aug 2012
Contoli M, Kraft M, Hamid Q, Bousquet J, Rabe K F, Fabbri L M, Papi A
Abstract excerpt
The role of small airway abnormalities in asthma pathogenesis has been extensively studied and debated for several decades. However, whether or not small airway abnormalities play a relevant role in specific phenotypes of asthmatic patients and contribute to clinical presentation is largely unknown. In the present review, we evaluated available data on the role of small airways in severe asthma, with a further...
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