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Article

Ruminant organotypic brain‐slice cultures as a model for the investigation of CNS listeriosis

18 Jul 2012

Abstract excerpt

Central nervous system (CNS) infections in ruminant livestock, such as listeriosis, are of major concern for veterinary and public health. To date, no host-specific in vitro models for ruminant CNS infections are available. Here, we established and evaluated the suitability of organotypic brain-slices of ruminant origin as in vitro model to study mechanisms of Listeria monocytogenes CNS infection. Ruminants are...

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PMID: 22804762
DOI: 10.1111/j.1365-2613.2012.00821.x

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