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Article

Mouse models for methylmalonic aciduria.

PloS one - 1 Jan 2012

Peters Heidi L, Pitt James J, Wood Leonie R, Hamilton Natasha J, Sarsero Joseph P, Buck Nicole E

Abstract excerpt

Methylmalonic aciduria (MMA) is a disorder of organic acid metabolism resulting from a functional defect of methylmalonyl-CoA mutase (MCM). MMA is associated with significant morbidity and mortality, thus therapies are necessary to help improve quality of life and prevent renal and neurological c...

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Identifiers

PMID: 22792386
DOI: 10.1371/journal.pone.0040609
PMCID: PMC3392231

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22792386-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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