Article
Phenotypic detection of metallo-β-lactamase in imipenem-resistant Pseudomonas aeruginosa.
TheScientificWorldJournal - 1 Jan 2012
Khosravi Yalda, Loke Mun Fai, Chua Eng Guan, Tay Sun Tee, Vadivelu Jamuna
Abstract excerpt
Carbapenems are the primary choice of treatment for severe Pseudomonas aeruginosa infection. However, the emergence of carbapenem resistance due to the production of metallo-β-lactamases (MBLs) is of global concern. In this study, 90 imipenem- (IPM- or IP-) resistant P. aeruginosa (IRPA) isolates, including 32 previously tested positive and genotyped for MBL genes by PCR, were subjected to double-disk synergy...
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