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Article

Retrograde signaling by the plastidial metabolite MEcPP regulates expression of nuclear stress-response genes.

Cell - 22 Jun 2012

Xiao Yanmei, Savchenko Tatyana, Baidoo Edward E K, Chehab Wassim E, Hayden Daniel M, Tolstikov Vladimir, Corwin Jason A, Kliebenstein Daniel J, Keasling Jay D, Dehesh Katayoon

Abstract excerpt

Plastid-derived signals are known to coordinate expression of nuclear genes encoding plastid-localized proteins in a process termed retrograde signaling. To date, the identity of retrograde-signaling molecules has remained elusive. Here, we show that methylerythritol cyclodiphosphate (MEcPP), a p...

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Identifiers

PMID: 22726439
DOI: 10.1016/j.cell.2012.04.038

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22726439-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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