Article
DELISHUS: an efficient and exact algorithm for genome-wide detection of deletion polymorphism in autism.
Bioinformatics (Oxford, England) - 15 Jun 2012
Aguiar Derek, Halldórsson Bjarni V, Morrow Eric M, Istrail Sorin
Abstract excerpt
MOTIVATION: The understanding of the genetic determinants of complex disease is undergoing a paradigm shift. Genetic heterogeneity of rare mutations with deleterious effects is more commonly being viewed as a major component of disease. Autism is an excellent example where research is active in identifying matches between the phenotypic and genomic heterogeneities. A considerable portion of autism appears to be...
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