Article
Apolipoprotein E/C1/C4/C2 gene cluster diversity in two native Andean populations: Aymaras and Quechuas.
Annals of human genetics - 1 Jul 2012
Gayà-Vidal Magdalena, Athanasiadis Georgios, Carreras-Torres Robert, Via Marc, Esteban Esther, Villena Mercedes, Vasquez René, Dugoujon Jean-Michel, Moral Pedro
Abstract excerpt
The APOE/C1/C4/C2 gene cluster presents high relevance in lipid metabolism and, therefore, has important epidemiological implications. Here, we study for the first time the variation patterns of 25 polymorphisms (10 short tandem repeats, STRs, and 15 single nucleotide polymorphismas, SNPs) in two native Andean samples from Bolivia (45 Aymaras and 45 Quechuas) as well as one European sample (n = 41) as external...
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