Article
Proteomic analysis of the function of spot in Helicobacter pylori anti-oxidative stress in vitro and colonization in vivo.
Journal of cellular biochemistry - 1 Nov 2012
Sun Yundong, Li Xinpeng, Li Wen, Zhao Min, Wang Lixiang, Liu Shili, Zeng Jiping, Liu Zhifang, Jia Jihui
Abstract excerpt
As a microaerobe, Helicobacter pylori employs the global regulator SpoT for defending against oxidative stress in vitro. However, the mechanisms how SpoT affects bacterial gene expression is still unknown. Moreover, the function of SpoT in H. pylori colonization in the host is remaining undetermined. To explore the functions of the SpoT in H. pylori pathogenesis, we constructed H. pylori 26695 spoT-deficient...
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