Article
Deep sequencing of the oral microbiome reveals signatures of periodontal disease.
PloS one - 1 Jan 2012
Liu Bo, Faller Lina L, Klitgord Niels, Mazumdar Varun, Ghodsi Mohammad, Sommer Daniel D, Gibbons Theodore R, Treangen Todd J, Chang Yi-Chien, Li Shan, Stine O Colin, Hasturk Hatice, Kasif Simon, Segrè Daniel, Pop Mihai, Amar Salomon
Abstract excerpt
The oral microbiome, the complex ecosystem of microbes inhabiting the human mouth, harbors several thousands of bacterial types. The proliferation of pathogenic bacteria within the mouth gives rise to periodontitis, an inflammatory disease known to also constitute a risk factor for cardiovascular disease. While much is known about individual species associated with pathogenesis, the system-level mechanisms...
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