Article
Does outdoor air pollution induce new cases of asthma? Biological plausibility and evidence; a review.
Respirology (Carlton, Vic.) - 1 Aug 2012
Gowers Alison M, Cullinan Paul, Ayres Jon G, Anderson H Ross, Strachan David P, Holgate Stephen T, Mills Inga C, Maynard Robert L
Abstract excerpt
It is widely accepted that air pollution can exacerbate asthma in those who already have the condition. What is less clear is whether air pollution can contribute to the initiation of new cases of asthma. Mechanistic evidence from toxicological studies, together with recent information on genes that predispose towards the development of asthma, suggests that this is biologically plausible, particularly in the...
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