Article
Cross talk between microRNA and coding cancer genes.
Cancer journal (Sudbury, Mass.) - 1 Jan 2000
Kunej Tanja, Godnic Irena, Horvat Simon, Zorc Minja, Calin George A
Abstract excerpt
MicroRNAs (miRNAs) are a class of noncoding RNAs (ncRNAs) and posttranscriptional gene regulators shown to be involved in pathogenesis of all types of human cancers. Their aberrant expression as tumor suppressors can lead to cancerogenesis by inhibiting malignant potential, or when acting as oncogenes, by activating malignant potential. Differential expression of miRNA genes in tumorous tissues can occur owing to...
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