Article
[Genetics of male infertility: the new players].
Medecine sciences : M/S - 1 May 2012
Coutton Charles, Satre Véronique, Arnoult Christophe, Ray Pierre
Abstract excerpt
Approximately 10-15% of couples experience infertility and male factors contribute to half of these cases. It was usually thought that infertility cannot be transmitted, but accumulating evidence indicates that many cases are indeed caused by genetic defects, some inherited. The use of single nucleotide polymorphisms (SNP) arrays allowing to genotype the totality of the genome recently led to identify several...
Topics
- Animals
- Aurora Kinases
- Chromosome Deletion
- Chromosomes, Human, Y
- Cystic Fibrosis Transmembrane Conductance Regulator
- Humans
- Infertility, Male
- Male
- Membrane Proteins
- Models, Biological
- Mutation